Opportunity

The health and biomedical research workforce will become truly diversified when socioeconomic barriers are overcome, allowing individuals from all backgrounds to become members and leaders of their fields. Focused opportunities must be provided for individuals from low-income and under-represented backgrounds, and the major goal is to ensure that individuals with interest and passion also have the skills, accomplishments, network, and support system required to succeed at each level of training.  We strive to provide these opportunities through our Johns Hopkins Initiative for Careers in Science and Medicine (CSM).

To date, the CSM Initiative has served over 580 scholars.  This includes 230 5th Graders (one-week science camp), 204 high schoolers (8-week summer internships with academic fortification), 101 undergraduates (10-week summer internships), and 46 post-baccalaureates (up to two-year mentored research-intensive training).  At least 83% of our high school scholars have matriculated into 4-year college programs and 73% have chosen STEM majors.  For our SARE program, at least 60% (87% of those confirmed) have graduated college by 6 years post-high school graduation. This compares quite favorably to the national  college complete rate of just 14% overall for students from this same socioeconomic background. For our postbaccalaureate scholars, 83% have been accepted into MD, MD/PhD, and PhD programs at a variety of institutions, including Hopkins, Stanford, Albert Einstein, Vanderbilt, Brown, Baylor, among many others.  11% have completed or are working towards their MS degree. 3% became research scientists, and 3% joined Teach for America to teach biology to high school students.

The CSM Initiative has been funded, in part, by a Health Careers Opportunity Program grant (non-renewable) through the Health Resources and Services Administration.  We also receive support from the Thomas Wilson Foundation, United Way of Central Maryland, Johns Hopkins School of Medicine, Johns Hopkins University, Camden Partners, Warnock Foundation,  Brancati Center, Sidney Kimmel Comprehensive Cancer Center, Toffler Family Charitable Trust, Bearman Foundation, Spudich Family, Joyce A. Robinson Living Trust, and Burroughs Wellcome Fund.  If you are interested in helping support the Johns Hopkins Initiative for Careers in Science and Medicine, please contact Doug Robinson (dnr@jhmi.edu), Sarah Farrell, Director of Development (sfarrell@jhmi.edu), or Kevin McGuire (kmcgui10@jhmi.edu), Sr. Associate Director of Development, Institute for Basic Biomedical Sciences.

Our Programs

News

July 21, 2017

The Careers in Science and Medicine went to the Hill to advocate for the Health Careers Opportunity Program, which supports... Read More

Example Publications Authored by CSM Scholars

Udyavar NR, Ahn J, Crepeau P, Morris-Wiseman LF, Thompson V, Chen Y, Segev DL, McAdams-DeMarco M, and Mathur A. Black patients are more likely to undergo parathyroidectomy for secondary hyperparathyroidism. Surgery 2022; https://doi.org/10.1016/j.surg.2022.05.040

Kernodle AB, Thompson V, Chen X, Norman S, Segev D, Purnell TS, McAdams-DeMarco M. Short Report: Race and Ethnicity Misclassification in Kidney Transplantation Research. Transplantation Direct, 2022; 8(10): e1373. DOI:10.1097/TXD.0000000000001373

Shawar AR, Truong PP, Shiffman J. The emergence of political priority for addressing child sexual abuse in the United Kingdom. Child Abuse & Neglect, 2022; 128: 105601. DOI: 10.1016/j.chiabu.2022.105601

Amorim MR, Aung O, Mokhlesi B, and Polotsky, VY. 2022. Leptin-mediated neural targets in obesity hypoventilation syndrome. Sleep, zsac153, https://doi.org/10.1093/sleep/zsac153.

Chen X, Liu Y, Thompson V, Chu NM, King EA, Walston JD, Kobashigawa JA, Dadhania DM, Segev DL, DeMarco MA. Transplant centers that assess frailty as part of clinical practice have better outcomes. BMC Geriatrics 2022; 22 (82): 1-12. DOI: 10.1186/s12877-022-02777-2

Hoskins VE, Smith K, Reddy KL. The shifting shape of genomes: dynamics of heterochromatin interactions at the nuclear lamina. Curr. Opin. Genet. Dev. 2021; 67: 163-173. doi: 10.1016/j.gde.2021.02.003.

Smith TA, Moore BN, Matoso A, Berkowitz DE, DeBerry JJ, Pluznick JL. Identification of novel bladder sensory GPCRs. Physiol. Rep. 2021; 9(8):e14840. doi: 10.14814/phy2.14840. 

Park J, Saha S, Chee B, Taylor J, Beach MC. Hidden in Plain Sight: Description of Stigmatizing Language in Patient Medical Records. JAMA Network Open (in press)

Beach MC, Park J, Han D, Evans C, Moore RD, Saha S. Clinician response to patient emotion: Impact on subsequent communication and visit length. Annals of Family Medicine (in press).

Mamo M, Ye IC, DiGiacomo JW, Park JY, Downs B, and Gilkes DM. Hypoxia alters the response to anti-EGFR therapy by regulating EGFR expression and downstream signaling in a DNA methylation-specific and HIF-dependent manner. Canc. Res. 2020, 80(22): 4998-5010.  DOI: 10.1158/0008-5472.CAN-20-1232

Bicket AK, Mihailovic A, Zheng C, Kashaf MS, Nagarajan N, Huang AS, Chapagain S, Da J, Ramulu PY. Comparison of patient-reported functional recovery from different types of ophthalmic surgery. Am J Ophthalmol. 2021 S0002-9394(21)00083-0. DOI: 10.1016/j.ajo.2021.02.018

Pilla, SJ, Park, J, Schwartz, JL, Albert, MC, Ephraim, PL, Boulware, LE, Mathioudakis, NN, Maruthur, NM, Beach, MC, Greer, RC. Hypoglycemia Communication in Primary Care Visits for Patients with Diabetes. J Gen Intern Med 2021; 1-10.  DOI: 10.1007/s11606-020-06385-x

Parajón E, Surcel A, Robinson DN. The Mechanobiome: A Goldmine for Cancer Therapeutics. Am. J. Physiol.-Cell Physiol. 2021; 320: C306-C323. doi: 10.1152/ajpcell.00409.2020

Yohannan J, Cheng M, Da J, Chapagain S, Sotimehin A, Bonham LW, Mihailovic A, Boland M, Ramulu P. Evidence-based criteria for determining peripapillary OCT reliability. Ophthalmology 2020; 127(2): 167-176. doi.org/10.1016/j.ophtha.2019.08.027

Park J, Saha S, Han D, Jindal M, Korthuis TK, Moore RD, Beach MC. Are clinicians’ empathic concern and perspective-taking traits associated with their response to patient emotions? Patient Education and Counseling 2020; 103(9):1745-1751.  DOI: 10.1016/j.pec.2020.04.016

Park J, Beach MC, Han D, Moore RD, Korthuis PT, Saha S. Racial disparities in clinician response to patient emotions. Patient Educ. Couns. 2020; 103(9):1736-1744. DOI: 10.1016/j.pec.2020.03.019

Flyak AI, Ruiz SE, Salas J, Rho S, Bailey JR, Bjorkman PJ. An ultralong CDRH2 in HCV neutralizing antibody demonstrates structural plasticity of antibodies against E2 glycoprotein. eLIFE 2020; 9: e53169. DOI: https://doi.org/10.7554/eLife.53169

Karaba AH, Figueroa A, Massaccesi G, Botto S, DeFilippis VR, Cox AL.Herpes simplex virus type 1 inflammasome activation in proinflammatory human macrophages is dependent on NLRP3, ASC, and caspase-1.  PLoS One 2020; 15(2): 1-18. doi.org/10.1371/journal.pone.0229570

DeLong K*, Bensouda S*, Zulfiqar F, Zierden HC, Hoang TM, Abraham AG, Coleman JS, Cone RA, Gravitt PE, Hendrix CW, Fuchs EJ, Gaydos CA, Weld ED, Ensign LM.  Conceptual Design of a Universal Donor Screening Approach for Vaginal Microbiota Transplant. Front. Cell. Infect. Microbiol. 2019, doi.org/10.3389/fcimb.2019.00306   *Co-first authors

Colbert MD, Flyak AI, Ogega CO, Kinchen VJ, Massaccesi G, Hernandez M, Davidson E, Doranz BJ, Cox AL, Crowe JE Jr, Bailey JR. Broadly Neutralizing Antibodies Targeting New Sites of Vulnerability in Hepatitis C Virus E1E2. J Virol. 2019 Jun 28;93(14). pii: e02070-18. PMID: 31068427

Little HC, Rodriguez S, Lei X, Tan SY, Steward AN, Sahagun A, Sarver DC, Wong GW. Myonectin deletion promotes adipose fat storage and reduces liver steatosis. FASEB J. 2019; 33: 1-22. PMID: 31002535

Blair AB*, Kleponis J*, Thomas DL 2nd*, Muth ST, Murphy AG, Kim V, Zheng L. IDO1 inhibition potentiates vaccine-induced immunity against pancreatic adenocarcinoma. J Clin Invest. 2019 Apr 1;129(4):1742-1755.  *Co-first authors.  PMID: 30747725

Goffigan-Holmes J, Sanabria D, DIaz J, Flock D, Chavez-Valdez R. Calbindin-1 Expression in the Hippocampus following Neonatal Hypoxia-Ischemia and Therapeutic Hypothermia and Deficits in Spatial Memory. Dev. Neurosci. 2019; 12:1-15. PMID: 30861522

Park J, Saha S, Han D, De Maesschalck S, Moore RD, Korthius PT, Roter D, Knowlton A, Woodson T, Beach MC. Emotional communication in HIV care: An observational study of patients’ expressed emotions and clinician response. AIDS and Behavior 2019; 23(10), 2816-2828. doi: 10.1007/s10461-019-02466-z

Kwaa AKR, Talana CAG, Blankson JN. Interferon alpha enhances NK cell function and the suppressive capacity of HIV-specific CD8+ T cells. J. Virol. 2019; 93(3): e01541-18. PMID: 30404799

Saung MT, Muth S, Ding D, Thomas DL 2nd, Blair AB, Tsujikawa T, Coussens L, Jaffee EM, Zheng L. Targeting myeloid-inflamed tumor with anti-CSF-1R antibody expands CD137+ effector T-cells in the murine model of pancreatic cancer. J. Immunother. Canc. 2018; 6(1): 118 (1-11). PMCID: PMC6234697

McAdams-DeMarco MA, Ying H, Thomas AG, Warsame F, Shaffer AA, Haugen CE, Garonzik-Wang JM, Desai NM, Varadhan R, Walston J, Norman SP, Segev DL. Frailty, Inflammatory Markers, and Waitlist Mortality Among Patients with End-Stage Renal Disease in a Prospective Cohort Study. Transplantation. 2018; 102(10):1740-1746. PMID: 29677074.

Chavez-Valdez R, Emerson P, Goffigan-Holmes J, Kirkwood A, Martin LJ, Northington FJ. Delayed injury of hippocampal interneurons after neonatal hypoxia-ischemia and therapeutic hypothermia in a murine model. Hippocampus. 2018;  28(8):617-630. PMID: 29781223.

Perez-Dulzaides R, Camacho E, Cordero RJB, Casadevall A. Cell-wall dyes interfere with Cryptococcus neoformans melanin deposition. Microbiology. 2018; 164(8):1012-1022. PMID: 29939127.

Osman G, Rodriguez J, Chan SY, Chisholm J, Duncan G, Kim N, Tatler AL, Shakesheff KM, Hanes J, Suk JS, Dixon JE. PEGylated enhanced cell penetrating peptide nanoparticles for lung gene therapy. J Control Release. 2018; 285: 35-45.  PMID: 30004000.

McAdams-DeMarco MA, Konel J, Warsame F, Ying H, González Fernández M, Carlson MC, Fine DM, Appel LJ, Segev DL. Intradialytic Cognitive and Exercise Training May Preserve Cognitive Function. Kidney Int Rep. 2017; 3(1):81-88. PMCID: PMC5762950.